• Event Date: November 10, 2014
  • Event Start Time: 12:00 PM
  • Event End Time: 7:00 PM
  • Event Location: Rutgers University, Department of Cell Biology and Neuroscience
  • Event Type: Human and Computer Vision Series
  • Event Semester: Fall 2014
  • Event Contact: Dr. David J. Margolis
  • Event Extra info: <a href="http://margolislab.cbn.rutgers.edu/">Dr. David J. Margolis</a>

My lab studies the neural circuitry that allows mice to detect sensory stimuli and perform sensory-guided discrimination tasks using their whiskers. I will discuss experiments in which mice are trained to discriminate rough and smooth textures in a Go-NoGo behavioral paradigm by licking for water rewards. Recent in vivo imaging results have identified distinct roles for neurons in primary somatosensory cortex (S1) that project to divergent cortical target areas, including secondary somatosensory cortex (S2) and primary motor cortex (M1). My presentation will focus on how activity changes occur in individual neurons and networks of cortical areas as mice learn this sensory-guided behavior, as well as on the in vivo neuroscience methods we use to measure and manipulate specific types of neurons.